Abstract: Filter feeding shellfish aquaculture is an important part of China's marine aquaculture industry, and suspended culture is the most important aquaculture method. Aquaculture facilities and shellfish sleeves placed at the sea surface can significantly reduce the surface water flow flux, thereby affecting water exchange and shellfish growth in the culture area. In order to explore the flow resistance effect of suspended mussel farm aquaculture facilities under different layout conditions, computational fluid dynamics (CFD) and using Large Eddy Simulation (LES) as the turbulence numerical mode to simulate the flow field effect of aquaculture facilities at five inflow angles and three farming spacings. The transport speed, transport flux and filterable water volume of each mussel sleeve are selected to evaluate the flow resistance effect. The results showed that under the influence of aquaculture facilities, the highest attenuation degree of the incoming flow speed in the farming range is 20.40%, and the vertical influence depth is 6~7 m. When the aquaculture facility is facing the current at an angle of 0°, the resistance effect is small, and when it turns to 45° and 90°, the reduction of the water transport flux caused by the aquaculture facility can reach up to 9.50%. Overall, the upstream angle of velocity attenuation is 90°>45°>30°>15°>0°.Due to the increase in the number of aquaculture facilities, the reduction of different upstream angles is different, so the cumulative effect of the resistance effect caused by different upstream angles should be considered when laying multiple aquaculture areas. When the spacing between shellfish sleeve is 0.80 and 0.70 m, the flow resistance effect of aquaculture facilities is less different under different inflow angle conditions, the transportation flux is correspondingly reduced by 0.02%-0.90%, the filterable rate volume remained at about 600 L/h.The flow resistance effect is more significant when the culture spacing decreased to 0.60 m, the transport flux is correspondingly reduced by 0.50%-2.20%,at this time the filterable rate is about 500 L/h. In terms of transport capacity of water volume, under different culture spacing, the transport capacity of upper layer is strong, and the transport capacity is weak at 30° and 45° inflow angles. The estimated results of the filterable water volume of each mussel sleeve show that it is higher under the condition of 15° facing current. In terms of filterable rate, the larger values of this index is concentrated at 0° and 15° upstream conditions, and a total of 16 and 21 in the four cases (a total of 32 points) appeared, respectively .Among the various upstream angles, the two off-site monitoring points (c4 and c8) recovered the fastest when the water is filtered at 0°, and although the recovery velocity is not as fast as when the 0° current is received, the filterable rate values of each detection point (c1-8) is relatively stable. When the incoming flow velocity increased from 0.5 m/s to 1.0 m/s, the amount of filterable rate per unit time of mussel sleeves increased by 1.7-2.5 times. Therefore, the comprehensive culturing interval is 0.7~0.8m, and the inflow angle is 0-15°. Research has shown that 0.7~0.8m is a relatively reasonable spacing for mussel suspended aquaculture. When the upstream angle of aquaculture facility is 15°, the filtrable water volume is better and the reduced flow velocity is smaller, which should ensure that fresh seawater can be obtained by the shell sleeves, so the optimal upstream angle is 0~15°. This study can provide scientific references for optimizing the layout of filter feeding shellfish aquaculture facilities and calculating aquaculture capacity. This study can provide scientific references for the optimization of the layout of filter-feeding shellfish culture facilities and the estimation of aquaculture capacity.